Cassiopeia vs Yasuo in Mid lane is a skill matchup on patch 26.16. The one thing to respect: respect his E → Q → Flash range — that's how he gets on top of you. Below is the exact page the OTP runs — runes, skill max order, summoner spells, item build and the four tips that decide the lane, plus a quick quiz before you lock in.

⇄ ChangeYOU · MIDCASSIOPEIAthe Serpent's Embrace

⇄ ChangeENEMY · MIDYASUOthe Unforgiven

VS

Skill matchupPre-6 MediumPost-6 MediumTake Teleport

How to play it

✓ DO

Respect E → Q

Keep distance from his E → Q → Flash range; if he E → Q's onto you, W → Flash or R → Flash backward.

Ult his E dash

R him mid-E animation for a guaranteed stun — but not if he's E'ing through you, and still watch for his Flash.

W your wave

W onto your minion wave to deny his dash mobility, and stand behind your casters so he can't reach you without E'ing in.

✕ DON'T

⛔

As you're about to get knocked up, don't cast anything but W on yourself or E — his ult is a blink.

Runes

SORCERY

PRECISIONuniversal page

SHARDS

No rune change for this matchup — run the universal page, our every-game default.

Spells

FLASH

TELEPORT

Items

Start

Core

→

→

16.14 Emerald+ - 53% WR - 474 games

Skill order

	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
		Q							Q	Q		Q	Q
			W											W	W		W	W
	E			E	E		E	E
						R					R					R

MAXE→Q→W

IMPROVE YOUR MACRO

Winning lane is only half the game — rotations, wave control and objective tempo decide the rest. Train the map on MOBA Trainer.

IMPROVE YOUR MACRO →