Cassiopeia vs Diana in Mid lane is a lane that swings with levels on patch 26.16. The one thing to respect: her all-in needs her Q to land — it resets her E, so bait it out and she has little threat. Below is the exact page the OTP runs — runes, skill max order, summoner spells, item build and the four tips that decide the lane, plus a quick quiz before you lock in.

⇄ ChangeYOU · MIDCASSIOPEIAthe Serpent's Embrace

⇄ ChangeENEMY · MIDDIANAScorn of the Moon

VS

Swings with levelsPre-6 EasyPost-6 MediumTake Teleport

How to play it

✓ DO

Bait her Q

Crescent Strike is what starts her all-in by resetting her E — while that Q is down she barely threatens you.

W then R post-6

When she has kill threat, open W into R: if she Q's or E's toward you she's stunned, if not she's slowed and grounded.

Outrange her E

Your max-range Q slightly outranges Lunar Rush, so poke with it and walk in and out to fish her Q.

✕ DON'T

⛔

Never try to reactively stun her mid-E — she can turn instantly on landing, so aim where she'll land instead.

Runes

SORCERY

PRECISIONuniversal page

SHARDS

No rune change for this matchup — run the universal page, our every-game default.

Spells

FLASH

TELEPORT

Items

Start

Core

→

→

Last 30 days Emerald+ - 48% WR - 1.1k games

Skill order

	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
		Q							Q	Q		Q	Q
			W											W	W		W	W
	E			E	E		E	E
						R					R					R

MAXE→Q→W

IMPROVE YOUR MACRO

Winning lane is only half the game — rotations, wave control and objective tempo decide the rest. Train the map on MOBA Trainer.

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