Cassiopeia vs Qiyana in Mid lane is a hard lane on patch 26.16. The one thing to respect: her R lands easily whenever she can reach you — save Flash or Zhonya's for its cast time. Below is the exact page the OTP runs — runes, skill max order, summoner spells, item build and the four tips that decide the lane, plus a quick quiz before you lock in.

⇄ ChangeYOU · MIDCASSIOPEIAthe Serpent's Embrace

⇄ ChangeENEMY · MIDQIYANAEmpress of the Elements

VS

Heavily unfavoredPre-6 HardPost-6 HardTake Teleport

How to play it

✓ DO

Answer her R

Her ult is easy to land once she's close, but its short cast time lets you Flash or Stopwatch/Zhonya's out.

Fish max-range Q

Poke with your farthest Q when she can't use both dashes and you aren't overextended.

Her W is readable

Terrashape needs a wall, brush, or river and can't cast from center lane, so you can predict her dash.

✕ DON'T

⛔

Never linger near walls when she has a gapclose and ult — that's a free full-duration R.

Runes

SORCERY

PRECISIONuniversal page

SHARDS

No rune change for this matchup — run the universal page, our every-game default.

Spells

FLASH

TELEPORT

Items

Start

Core

→

→

Last 30 days Emerald+ - 49% WR - 768 games

Skill order

	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
		Q							Q	Q		Q	Q
			W											W	W		W	W
	E			E	E		E	E
						R					R					R

MAXE→Q→W

IMPROVE YOUR MACRO

Winning lane is only half the game — rotations, wave control and objective tempo decide the rest. Train the map on MOBA Trainer.

IMPROVE YOUR MACRO →