Cassiopeia vs Akali in Mid lane is a skill matchup on patch 26.16. The one thing to respect: her W (Twilight Shroud) is her main threat — play aggressive while it's on cooldown. Below is the exact page the OTP runs — runes, skill max order, summoner spells, item build and the four tips that decide the lane, plus a quick quiz before you lock in.

⇄ ChangeYOU · MIDCASSIOPEIAthe Serpent's Embrace

⇄ ChangeENEMY · MIDAKALIthe Rogue Assassin

VS

Skill matchupPre-6 MediumPost-6 MediumTake Teleport

How to play it

✓ DO

Punish her W

Her W (Twilight Shroud) is her main threat — while it's down (20s CD) you're free to play aggressive.

Fish max-range Q

Post-6, fish for max-ranged Q's, then chain E's and autos — don't chase too far.

Ult her E return

When her second E lands her in front of you and her dashes are on CD, ult for a guaranteed stun.

✕ DON'T

⛔

Never keep fighting inside her W — she gains move speed and safety there; wait for it to drop.

Runes

SORCERY

PRECISIONuniversal page

SHARDS

No rune change for this matchup — run the universal page, our every-game default.

Spells

FLASH

TELEPORT

Items

Start

Core

→

→

16.14 Emerald+ - 47% WR - 301 games

Skill order

	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
		Q							Q	Q		Q	Q
			W											W	W		W	W
	E			E	E		E	E
						R					R					R

MAXE→Q→W

IMPROVE YOUR MACRO

Winning lane is only half the game — rotations, wave control and objective tempo decide the rest. Train the map on MOBA Trainer.

IMPROVE YOUR MACRO →