Cassiopeia vs Anivia in Mid lane is a skill matchup on patch 26.16. The one thing to respect: her slow-traveling Q is her main threat — dodging it comes before anything else. Below is the exact page the OTP runs — runes, skill max order, summoner spells, item build and the four tips that decide the lane, plus a quick quiz before you lock in.

⇄ ChangeYOU · MIDCASSIOPEIAthe Serpent's Embrace

⇄ ChangeENEMY · MIDANIVIAthe Cryophoenix

VS

Skill matchupPre-6 MediumPost-6 MediumTake Teleport

How to play it

✓ DO

Dodge her Q

Her slow-traveling Q is her main threat — sidestep it, since her E barely hurts unless it connects first.

Ult cancels her ult

Land your poison and especially your ult stun to cancel her Glacial Storm — she needs it for most of her damage, so you can still fight back.

Kill the egg

During lane her egg has less resistances, so don't burn all your mana killing her while rebirth is up — pop the egg instead.

✕ DON'T

⛔

Never waste all your mana trying to kill her while her rebirth passive is still up.

Runes

SORCERY

PRECISIONuniversal page

SHARDS

No rune change for this matchup — run the universal page, our every-game default.

Spells

FLASH

TELEPORT

Items

Start

Core

→

→

Last 30 days Emerald+ - 51% WR - 894 games

Skill order

	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
		Q							Q	Q		Q	Q
			W											W	W		W	W
	E			E	E		E	E
						R					R					R

MAXE→Q→W

IMPROVE YOUR MACRO

Winning lane is only half the game — rotations, wave control and objective tempo decide the rest. Train the map on MOBA Trainer.

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