Cassiopeia vs Irelia in Mid lane is a skill matchup on patch 26.16. The one thing to respect: her E is her main threat — with her Q also up you can't step toward her or any minion she can dash to. Below is the exact page the OTP runs — runes, skill max order, summoner spells, item build and the four tips that decide the lane, plus a quick quiz before you lock in.

⇄ ChangeYOU · MIDCASSIOPEIAthe Serpent's Embrace

⇄ ChangeENEMY · MIDIRELIAthe Blade Dancer

VS

Skill matchupPre-6 MediumPost-6 MediumTake Teleport

How to play it

✓ DO

Respect her E

Her E is her main threat unless her Q is down — with both up, don't approach her or any minion she can Q to unless you W her or you're at tower.

Punish a resetless Q

If she Q's anything without a reset she's very vulnerable until it's back — and since her Q travels through you, cast your spells slightly behind yourself.

W her destination

Against her dashes, W or Q her destination immediately instead of reacting, and W your own wave to cut her mobility.

✕ DON'T

⛔

Never linger inside her R → Flash range when it's a threat — that combo reaches further than it looks and sets up her E.

Runes

SORCERY

PRECISIONuniversal page

SHARDS

No rune change for this matchup — run the universal page, our every-game default.

Spells

FLASH

TELEPORT

Items

Start

Core

→

→

16.14 Emerald+ - 51% WR - 295 games

Skill order

	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
		Q							Q	Q		Q	Q
			W											W	W		W	W
	E			E	E		E	E
						R					R					R

MAXE→Q→W

IMPROVE YOUR MACRO

Winning lane is only half the game — rotations, wave control and objective tempo decide the rest. Train the map on MOBA Trainer.

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