Ryze vs Lissandra in Mid lane is a favourable lane on patch 26.16. The one thing to respect: her W root is her only real setup — don't let her land it on you. Below is the exact page the OTP runs — runes, skill max order, summoner spells, item build and the four tips that decide the lane, plus a quick quiz before you lock in.

⇄ ChangeYOU · MIDRYZEthe Rune Mage

⇄ ChangeENEMY · MIDLISSANDRAthe Ice Witch

VS

Favors youPre-6 EasyPost-6 EasyTake Teleport

How to play it

✓ DO

Don't get W-rooted

Her Ring of Frost root is the one thing that beats you — stay spaced so she can't land it.

Trade and extend

Trade aggressively and extend every trade — you out-damage her outright and destroy her in lane.

Sidestep her Q

Dodge her Q — it's her main poke and easy to walk out of.

✕ DON'T

⛔

Never walk into her W root — it's the only opening she gets on you.

Runes

SORCERYmatchup page

RESOLVEoverride for this matchup

SHARDS

Matchup-specific rune page — override from the OTP sheet for this lane.

Spells

FLASH

TELEPORT

Items

Start

Core

→

→

16.14 Emerald+ - 49% WR - 422 games

Skill order

	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
	Q			Q	Q		Q	Q
			W											W	W		W	W
		E							E	E		E	E
						R					R					R

MAXQ→E→W

IMPROVE YOUR MACRO

Winning lane is only half the game — rotations, wave control and objective tempo decide the rest. Train the map on MOBA Trainer.

IMPROVE YOUR MACRO →