Ryze vs Annie in Mid lane is a lane that swings with levels on patch 26.16. The one thing to respect: when she drops Tibbers, kite out — that's her 100-to-0 window. Below is the exact page the OTP runs — runes, skill max order, summoner spells, item build and the four tips that decide the lane, plus a quick quiz before you lock in.

⇄ ChangeYOU · MIDRYZEthe Rune Mage

⇄ ChangeENEMY · MIDANNIEthe Dark Child

VS

Swings with levelsPre-6 HardPost-6 MediumTake Teleport

How to play it

✓ DO

Kite out Tibbers

When she summons Tibbers, kite out — that's her all-in to 100-to-0 you.

Win after level 10

Once you hit level 10 she can't 100-to-0 you anymore, and that's when you win hard.

Play safe early

She wins trades hard early and sets up easy ganks for her jungler — farm safe until you spike.

✕ DON'T

⛔

Trade with her before level 10 — she wins early exchanges hard and can 100-to-0 you.

Runes

SORCERYmatchup page

RESOLVEoverride for this matchup

SHARDS

Matchup-specific rune page — override from the OTP sheet for this lane.

Spells

FLASH

TELEPORT

Items

Start

Core

→

→

Last 30 days Emerald+ - 44% WR - 1.2k games

Skill order

	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
	Q			Q	Q		Q	Q
			W											W	W		W	W
		E							E	E		E	E
						R					R					R

MAXQ→E→W

IMPROVE YOUR MACRO

Winning lane is only half the game — rotations, wave control and objective tempo decide the rest. Train the map on MOBA Trainer.

IMPROVE YOUR MACRO →