Matchups › Yasuo › vs Lissandra

Yasuo vs Lissandra

YasuoYOU · MID
LissandraENEMY · MID
VS
Heavily unfavoredPre-6 HardPost-6 HardTake Ignite

How to play it

Dodge her Q shatter
You have to position awkwardly to avoid the shatter of her spammable Q: Yasuo hates CC and she has plenty of it.
Only kill pre-6
If you see a clear opening pre-6 you can go for it; otherwise stick to farming and scaling.
Don't dive her
Jump on her and she just W's and walks away or E's out: she'll cockblock every engage.
Never force a jump onto her: she'll simply W and walk off or E away and leave you exposed.
Runes
PRECISIONPRECISION
Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Absorb Life
Triumph
Presence of Mind
Legend: Alacrity
Legend: Haste
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
RESOLVERESOLVE
Demolish
Font of Life
Shield Bash
Conditioning
Second Wind
Bone Plating
Overgrowth
Revitalize
Unflinching
SHARDS
Adaptive
Attack Speed
Ability Haste
Adaptive
Move Speed
Health Scaling
Health +65
Tenacity
Health Scaling
Spells
FlashFLASH
IgniteIGNITE
Items
Start
Core
16.14 Emerald+ - 46% WR - 2.2k games
Skill order
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QQQQQ
WWWWW
EEEEE
RRR
MAXQQEEWW
Yasuo · Mid · Patch 26.17 · Ranked Solo · Updated Sep 5, 2026

Yasuo vs Lissandra in Mid lane is a hard lane on patch 26.17. The one thing to respect: her spammable Q shatter is the CC you must never eat, position awkwardly to dodge it.

Yasuo matchup data compiled from the community contribution of Yasuo OTPsLeague of Legends assets © Riot Games (Data Dragon).