Matchups › Tryndamere › vs Vayne

Tryndamere vs Vayne

TryndamereYOU · TOP
VayneENEMY · TOP
VS
Heavily unfavoredPre-6 HardPost-6 HardTake Ignite

How to play it

Respect her Condemn
Her Condemn (E) knocks you away and can pin you to a wall: it's a 20s cooldown at level 1, so force it out before you commit.
Trade in your wave
Don't chase: trade inside your own minions so she takes wave damage; let her auto you in minion-aggro range where you out-sustain her.
Set up ganks
She's very susceptible to ganks ('Vayne top treatment'): hold your summoners when alone, keep your HP high and let your jungler snowball the lane.
Never fight Vayne straight up in lane: you don't win unless you're ahead; trade only inside your wave or catch her from fog.
Runes
DOMINATIONDOMINATION
Electrocute
Dark Harvest
Hail of Blades
Cheap Shot
Taste of Blood
Sudden Impact
Sixth Sense
Grisly Mementos
Deep Ward
Treasure Hunter
Relentless Hunter
Ultimate Hunter
PRECISIONPRECISION
Absorb Life
Triumph
Presence of Mind
Legend: Alacrity
Legend: Haste
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
SHARDS
Adaptive
Attack Speed
Ability Haste
Adaptive
Move Speed
Health Scaling
Health +65
Tenacity
Health Scaling
Spells
FlashFLASH
IgniteIGNITE
Items
Start
Core
16.14 Emerald+ - 53% WR - 764 games
Skill order
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QQQQQ
WWWWW
EEEEE
RRR
MAXQQEEWW
Tryndamere · Top · Patch 26.17 · Ranked Solo · Updated Sep 5, 2026

Tryndamere vs Vayne in Top lane is a hard lane on patch 26.17. The one thing to respect: force out her Condemn, it's a long cooldown, and once it's down she can't peel your all-in.

Tryndamere matchup data compiled from the group contribution of Challenger Tryndamere OTPsLeague of Legends assets © Riot Games (Data Dragon).