Matchups › Sylas › vs Syndra

Sylas vs Syndra

SylasYOU · MID
SyndraENEMY · MID
VS
Skill matchupPre-6 MediumPost-6 MediumTake Ignite

How to play it

Bait her E
Her E is her one hard engage-stopper: throw out E1 to bait it, and only commit once it's gone.
Engage with E2
With her E spent, engage with E2: and press it in the mid game, where you're the stronger of two strong scalers.
Skip her ult
Don't rush to steal her R: on Sylas it's base damage only since you hold zero spheres, so it hits weak.
Never engage with E2 before her E is baited out: walking your all-in into her stun throws the trade.
Runes
DOMINATIONDOMINATION
Electrocute
Dark Harvest
Hail of Blades
Cheap Shot
Taste of Blood
Sudden Impact
Sixth Sense
Grisly Mementos
Deep Ward
Treasure Hunter
Relentless Hunter
Ultimate Hunter
RESOLVERESOLVE
Demolish
Font of Life
Shield Bash
Conditioning
Second Wind
Bone Plating
Overgrowth
Revitalize
Unflinching
SHARDS
Adaptive
Attack Speed
Ability Haste
Adaptive
Move Speed
Health Scaling
Health +65
Tenacity
Health Scaling
Spells
FlashFLASH
IgniteIGNITE
Items
Start
Core
16.14 Emerald+ - 53% WR - 2.1k games
Skill order
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QQQQQ
WWWWW
EEEEE
RRR
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Sylas · Mid · Patch 26.17 · Ranked Solo · Updated Sep 5, 2026

Sylas vs Syndra in Mid lane is a skill matchup on patch 26.17. The one thing to respect: her E is her one hard CC, bait it with E1 before you commit.

Sylas matchup data compiled from the community Sylas OTP sheet.League of Legends assets © Riot Games (Data Dragon).