Matchups › Gwen › vs Vayne
MATCHUPGwen · Top · Patch 26.17 · Ranked Solo · Updated Aug 26, 2026

Gwen vs Vayne in Top lane is a hard lane on patch 26.17. The one thing to respect: her Condemn is her setup — W through it for your only all-in window, and don't force the fight otherwise. Below is the exact page the OTP runs — runes, skill max order, summoner spells, item build and the four tips that decide the lane, plus a quick quiz before you lock in.

GwenYOU · TOPGWENThe Hallowed Seamstress
VayneENEMY · TOPVAYNEthe Night Hunter
VS
Heavily unfavoredPre-6 HardPost-6 HardTake Ignite
How to play it
DO
W her Condemn
After 6, if she E's you you can W it and look for an all-in — but stealth plus ghost/flash make it a coin-flip, so don't force it.
Poke, then all-in
Trade on your W cooldown when she can't hit back, and only all-in once you've poked her low enough.
Give up CS safely
Let her auto you once to push the wave, then farm safely under tower — give up CS if you must.
DON'T
Never look to fight her in lane — even an all-in that wins on paper usually loses to her stealth and ghost/flash.
Runes
PRECISIONPRECISION
Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Absorb Life
Triumph
Presence of Mind
Legend: Alacrity
Legend: Haste
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
RESOLVERESOLVEuniversal page
Demolish
Font of Life
Shield Bash
Conditioning
Second Wind
Bone Plating
Overgrowth
Revitalize
Unflinching
SHARDS
Adaptive
Attack Speed
Ability Haste
Adaptive
Move Speed
Health Scaling
Health +65
Tenacity
Health Scaling
No rune change for this matchup — run the universal page, our every-game default.
Spells
FlashFLASH
IgniteIGNITE
Items
Start
Core
16.14 Emerald+ - 51% WR - 449 games
Skill order
123456789101112131415161718
QQQQQ
WWWWW
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RRR
MAXQQEEWW

IMPROVE YOUR MACRO

Winning lane is only half the game — rotations, wave control and objective tempo decide the rest. Train the map on MOBA Trainer.
IMPROVE YOUR MACRO →
Gwen matchup data compiled from the Gwen OTP community matchup sheetLeague of Legends assets © Riot Games (Data Dragon).