Matchups › Ekko › vs Karthus
MATCHUPEkko · Mid · Patch 26.14 · Ranked Solo · Updated Jul 22, 2026

Ekko vs Karthus in Mid lane is a favourable lane on patch 26.14. The one thing to respect: his damage over time wins long fights — keep every trade short. Below is the exact page the OTP runs — runes, skill max order, summoner spells, item build and the four tips that decide the lane, plus a quick quiz before you lock in.

EkkoYOU · MIDEKKOthe Boy Who Shattered Time
KarthusENEMY · MIDKARTHUSthe Deathsinger
VS
Favors youPre-6 EasyPost-6 EasyTake Ignite
How to play it
DO
Don't sit in Defile
His Defile grinds you down over time, so keep trades short and never linger in the aura.
Fight after level 2
Trade with W from level 2 on — you win the 1v1 unless he's a full item ahead.
Zhonya's for his ult
Pick up a Zhonya's later so you can survive his Requiem in fights.
DON'T
Never grind out a long, extended trade — his damage over time beats you there.
Runes
DOMINATIONDOMINATION
Electrocute
Dark Harvest
Hail of Blades
Cheap Shot
Taste of Blood
Sudden Impact
Sixth Sense
Grisly Mementos
Deep Ward
Treasure Hunter
Relentless Hunter
Ultimate Hunter
SORCERYSORCERYuniversal page
Axiom Arcanist
Manaflow Band
Nimbus Cloak
Transcendence
Celerity
Absolute Focus
Scorch
Waterwalking
Gathering Storm
SHARDS
Adaptive
Attack Speed
Ability Haste
Adaptive
Move Speed
Health Scaling
Health +65
Tenacity
Health Scaling
No rune change for this matchup — run the universal page, our every-game default.
Spells
FlashFLASH
IgniteIGNITE
Items
Start
Core
Last 30 days Emerald+ - 56% WR - 780 games
Skill order
123456789101112131415161718
QQQQQ
WWWWW
EEEEE
RRR
MAXQQEEWW

IMPROVE YOUR MACRO

Winning lane is only half the game — rotations, wave control and objective tempo decide the rest. Train the map on MOBA Trainer.
IMPROVE YOUR MACRO →
Ekko matchup data made by the group contribution of Ekko OTP mainsLeague of Legends assets © Riot Games (Data Dragon).