Akali vs Cassiopeia in Mid lane is a skill matchup on patch 26.14. The one thing to respect: her Q is the hit that kills you — every Q that lands is about half your HP, so dodging it is everything. Below is the exact page the OTP runs — runes, skill max order, summoner spells, item build and the four tips that decide the lane, plus a quick quiz before you lock in.

⇄ ChangeYOU · MIDAKALIthe Rogue Assassin

⇄ ChangeENEMY · MIDCASSIOPEIAthe Serpent's Embrace

VS

Skill matchupPre-6 MediumPost-6 MediumTake Ignite

How to play it

✓ DO

Dodge her Q

On lane her Q matters by far the most — every one that lands is roughly half your HP; dodge it and she's weak.

All-in when forward

If she's pushed up the lane, all-in her — otherwise she'll poke you to death.

Don't outlast her mana

She has infinite mana — don't count on her running out; force a play instead.

✕ DON'T

⛔

Never try to outlast her mana — she never runs out; make your play when she over-extends.

Runes

DOMINATION

RESOLVEuniversal page

SHARDS

No rune change for this matchup — run the universal page, our every-game default.

Spells

FLASH

IGNITE

Items

Start

Core

→

→

16.14 Emerald+ - 58% WR - 383 games

Skill order

	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
	Q			Q	Q		Q	Q
			W											W	W		W	W
		E							E	E		E	E
						R					R					R

MAXQ→E→W

IMPROVE YOUR MACRO

Winning lane is only half the game — rotations, wave control and objective tempo decide the rest. Train the map on MOBA Trainer.

IMPROVE YOUR MACRO →